Function:
X inactivation is developed early in mammalian females that transcriptionally silence one of the X chromosomes, which results in dosage equivalence in males and females. The process depends on multiple factors, such as the region of chromosome X which is also called the X inactivation centre (XIC). The XIC compromises sever non coding and protein-coding genes .Xis gene was the first gene to be identified with the X inactivation Centre. This gene is expressed solely from the XIC of the inactive X chromosome, and is needed for the spread of the X-inactivation.
How can Xist be used in order to treat chromosome disorders?
ReplyDeleteWhat happens to the female more specifically when they have the Xist gene?
Can the Xist gene be used to silence other chromosomes, other then the X chromosome.
1) What are familial skewed and craniofrontnasal dysplasia?
ReplyDelete2) How does the Xist gene silence chromosomes?
3) How can the Xist gene be used to treat chromosome disorders?
1. How can you use Xist to treat chromosome disorders?
ReplyDelete2. How are the XIC and the Xis different?
3. How does the silencing of the chromosome work?
Q1: What does it mean to 'transcriptionally silence' a chromosome?
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